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Ulrich Schraermeyer Selected Research

soraprazan

1/2022Removal of RPE lipofuscin results in rescue from retinal degeneration in a mouse model of advanced Stargardt disease: Role of reactive oxygen species.
1/2022Remofuscin induces xenobiotic detoxification via a lysosome-to-nucleus signaling pathway to extend the Caenorhabditis elegans lifespan.
12/2020Penetration, distribution, and elimination of remofuscin/soraprazan in Stargardt mouse eyes following a single intravitreal injection using pharmacokinetics and transmission electron microscopic autoradiography: Implication for the local treatment of Stargardt's disease and dry age-related macular degeneration.

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Ulrich Schraermeyer Research Topics

Disease

14Macular Degeneration (Age-Related Maculopathy)
01/2022 - 05/2002
4Stargardt Disease
01/2022 - 08/2013
4Choroidal Neovascularization
11/2020 - 10/2002
3Eye Diseases (Eye Disease)
01/2022 - 02/2013
3Blindness (Hysterical Blindness)
12/2020 - 10/2012
3Ganglion Cysts (Ganglion)
12/2015 - 12/2007
2Retinal Degeneration
01/2022 - 10/2002
2Rupture
01/2018 - 10/2002
2Retinoblastoma (Glioblastoma, Retinal)
01/2017 - 11/2016
2Inflammation (Inflammations)
12/2016 - 07/2002
1Neurodegenerative Diseases (Neurodegenerative Disease)
01/2022
1Demyelinating Diseases (Demyelinating Disease)
11/2019
1Refractive Errors (Refractive Error)
11/2019
1Myopia
11/2019
1Hypoxia (Hypoxemia)
01/2019
1Cerebral Malaria
01/2019
1Intussusception
01/2019
1Malaria
01/2019
1Endophthalmitis (Ophthalmia)
12/2016
1Arthrogryposis renal dysfunction cholestasis syndrome
02/2016
1Hemolysis
06/2014
1Hypertrophy
06/2014
1Retinal Diseases
08/2013
1Thrombotic Microangiopathies
09/2012
1Papilledema
07/2008
1Glaucoma
12/2007
1Macular Edema
06/2007
1Atrophy
02/2007
1Ischemia
11/2006
1Blister (Bulla)
11/2006
1Retinal Detachment (Retinal Detachments)
11/2006
1Leukostasis
09/2004
1Diabetic Retinopathy (Retinopathy, Diabetic)
09/2004
1Cicatrix (Scar)
12/2003

Drug/Important Bio-Agent (IBA)

9Retinaldehyde (Retinal)IBA
01/2022 - 09/2004
7LipofuscinIBA
01/2022 - 01/2011
6Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
11/2020 - 10/2007
4Bevacizumab (Avastin)FDA Link
11/2020 - 06/2007
3soraprazanIBA
01/2022 - 12/2020
3Retinal Pigments (Pigments, Visual)IBA
01/2017 - 05/2002
2Trace Elements (Biometals)IBA
01/2018 - 07/2011
2Ranibizumab (Lucentis)FDA Link
06/2014 - 10/2007
2Proteins (Proteins, Gene)FDA Link
06/2014 - 07/2002
2Melanins (Melanin)IBA
08/2013 - 10/2005
1Reactive Oxygen Species (Oxygen Radicals)IBA
01/2022
1Biomarkers (Surrogate Marker)IBA
11/2019
1Tyrosine (L-Tyrosine)FDA Link
01/2017
1hydroxide ionIBA
01/2017
1RetinoidsIBA
01/2017
1Immunoglobulin Fc FragmentsIBA
12/2016
1Eosine Yellowish-(YS) (Eosin)IBA
11/2016
1Hematoxylin (Haematoxylon)IBA
11/2016
1Lipid Bilayers (Lipid Bilayer)IBA
02/2016
1IronIBA
08/2015
1afliberceptIBA
06/2014
1Antigen-Antibody Complex (Immune Complex)IBA
09/2012
1ZincIBA
07/2011
1Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
07/2008
1neogeninIBA
12/2007
1AntigensIBA
10/2007
1SolutionsIBA
11/2006
1Edetic Acid (EDTA)FDA Link
11/2006
1Saline SolutionIBA
11/2006
1Cell Adhesion MoleculesIBA
09/2004
1Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
09/2004
1Platelet Endothelial Cell Adhesion Molecule-1IBA
12/2003
1Peroxidase (Myeloperoxidase)IBA
12/2003
1Dextrans (Dextran)FDA Link
12/2003
1fluorescein isothiocyanate dextranIBA
12/2003
1Rhodopsin (Visual Purple)IBA
10/2002
1Oxygen (Dioxygen)IBA
10/2002

Therapy/Procedure

4Intravitreal Injections
01/2022 - 09/2012
2Therapeutics
01/2017 - 10/2007
2Lasers (Laser)
12/2003 - 10/2002
2Transplantation
10/2002 - 05/2002
1Lenses
11/2019
1Radiotherapy
01/2017
1Microelectrodes
12/2015
1Vitrectomy
11/2006
1Autologous Transplantation
10/2002